Antibiotic Resistance Monitoring in Ocular Microorganisms

Posted by Tracy Hendershott on Nov 26, 2018 9:00:00 AM
Tracy Hendershott
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In the realm of infectious disease, antibiotic resistance is a real and ever increasing concern across the entire healthcare industry.  This is also true for ocular infections.  With bacterial conjunctivitis being the second most common cause (versus viral conjunctivitis), diligent epidemiology and surveillance monitoring brings valued insight to us all.  Eurofins Central Laboratory is proud to have provided analytical services (microbiological species confirmation and antibiotic resistance profile determination) to one of the only two nationwide multi-center surveillance studies (Antibiotic Resistance Monitoring in Ocular Microorganisms - ARMOR) ever undertaken in this indication. Article can be downloaded here.

Species identification was provided for Staphylococcus aureus, Coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa and Haemophilius influenza.  Antibiotic resistance profile determination was provided for fluoroquinolones (ciprofloxacin, moxifloxacin, gatifloxacin, besifloxacin, levofloxacin and ofloxacin), macrolides (azithromycin), aminoglycosides (tobramycin), lincosamides (clindamycin), penicillins (oxacillin and/or penicillin), dihydrofolate reductase inhibitors (trimethoprim), polypeptides (polymyxin B), amphenicols (chloramphenicol), tetracyclines (tetracycline) and glycopeptides (vancomycin).  

Eurofins Central Laboratory is one of the six divisions within Eurofins BioPharma Services (Early Development, Bioanalytical, Genomics, Virology/Immunology, Oncology/Pathology, Central Laboratory) that provides true end-to-end analytical services for your clinical trial development needs. 

If your passion and professional dedication is within the Infectious Disease category, and/or Ophthalmology, we look forward to the opportunity to support your advancements in this critical indication.  Please reach out to us here and we can begin the conversation. 

 

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BIBLIOGRAPHY:

Asbell PA, DeCory HH (2018) Antibiotic resistance among bacterial conjuctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study. PLoS ONE 13(10): e0205814. https://doi.org/10.1371/journal.pone.0205814 
Link to CC license:
https://creativecommons.org/licenses/by/4.0/legalcode
No revisions have been made to the original article.

 

Tags: Drug Development, Clinical Trial, Bioanalytical Testing